He received his Ph.D. from Yale University School of Medicine with Dr. Benjamin S. Bunney and had postdoctoral training with Dr. Rodolfo Llinas in the Department of Physiology and Biophysics at New York University School of Medicine.  Dr. Grace has been involved in translational research related to the dopamine system for over 30 years.   His early work pioneered the identification and characterization of dopamine-containing neurons, and was the first to provide a means to quantify their activity state and pattern in a way that is the standard in the literature, all while working as a graduate student.  His current work involves looking at the interactions of several brain regions with known involvement in schizophrenia and drug abuse, including  the hippocampus, prefrontal cortex, and amygdala, and how these interactions are disrupted by stress.  Dr. Grace has received several awards for his research, including the Paul Janssen Schizophrenia Research Award and the Lilly Basic Scientist Award from the International College of Neuropsychopharmacology, the Efron Award from the American College of Neuropsychopharmacology, as well as a NIMH MERIT award, a Distinguished Investigator award from the National Alliance for Research in Schizophrenia and Depression, the Judith Silver Memorial Investigator Award from the National Alliance for the Mentally Ill, and appointment as a Distinguished Professor of Neuroscience at the University of Pittsburgh.  Dr. Grace was also recently elected as a Fellow in the American Association for the Advancement of Science.  He is also a past member of the governing council of the American College of Neuropsychopharmacology and editor on numerous leading journals in the field. Dr. Grace’s work has had a substantial impact on the field that has spanned basic neuroscience and clinical research.  His work is unique in providing a systems neuroscience approach to the understanding of complex psychiatric disorders in humans.  Most significantly, he is one of a handful of individuals that not only performs important basic research, but has the ability to integrate this work into testable models of relevance to the human condition.